Getting Started
Indices
Inflammation
Bone and mineral
Glucose and insulin
Lipids
Nerve and blood vessel
Oxidative stress and fibrosis
Kidney and protein
Cartilage
CTX-II
C-terminal cross-linked telopeptide of type II collagen
High
510.7pg·mL⁻¹Ref 120–450 pg·mL⁻¹
Z +2.74↑ Bad
The card shows an example result of 510.7 pg·mL⁻¹, which is 2.74 SD above the mean.
What it measures
Type II collagen is the main structural protein in joint cartilage. CTX-II is a piece released when it breaks down, so it tracks cartilage loss.
Reference range
| Field | Value |
|---|---|
| Abbreviation | CTX-II |
| Group | Bone and mineral |
| Unit | pg·mL⁻¹ |
| Healthy range | 120–450 |
| Mean | 285 |
| SD | 82.5 |
| Direction | ↑ Bad — a raised value is the concern. |
The mean is (low + high) / 2 and the SD is (high − low) / 4, so the healthy range covers Z from −2 to +2.
Reading the result
- High — Points to faster cartilage breakdown, as in osteoarthritis.
- Low — Not a concern.
Notes
- Often measured in urine. These values are for serum.
- Results vary with time of day, so test at the same time each time.
- This page is general information, not medical advice. Discuss results with a clinician.