CTX-II
C-terminal cross-linked telopeptide of type II collagen
High
510.7pg·mL⁻¹Ref 120–450 pg·mL⁻¹
Z +2.74↑ Bad

The card shows an example result of 510.7 pg·mL⁻¹, which is 2.74 SD above the mean.

What it measures

Type II collagen is the main structural protein in joint cartilage. CTX-II is a piece released when it breaks down, so it tracks cartilage loss.

Reference range

FieldValue
AbbreviationCTX-II
GroupBone and mineral
Unitpg·mL⁻¹
Healthy range120–450
Mean285
SD82.5
Direction↑ Bad — a raised value is the concern.

The mean is (low + high) / 2 and the SD is (high − low) / 4, so the healthy range covers Z from −2 to +2.

Reading the result

  • High — Points to faster cartilage breakdown, as in osteoarthritis.
  • Low — Not a concern.

Notes

  • Often measured in urine. These values are for serum.
  • Results vary with time of day, so test at the same time each time.
  • This page is general information, not medical advice. Discuss results with a clinician.